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6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one Isithombe Esifakiwe
  • 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one
  • 6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one

6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one

Incazelo emfushane:

Igama lekhemikhali:6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one

I-CAS: 1256578-99-0

Ifomula yekhemikhali: C13H15BRO2

Isisindo se-molecule: 283.16

Ukuminyana:1.3±0.1g/cm3

Iphoyinti elibilayo: 354.7±42.0 ℃ (760 mmHg)

 


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Incazelo Yomkhiqizo

Izimo zamakhemikhali

6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-one iwuketshezi olusobala olungenambala ukuya kokuphuzi ngokukhanyayo, olungancibiliki emanzini, oluncibilika ku-CHCl3, isitoreji kufanele sibe yiqhwa, sihlukaniswe nama-oxidants, amakhemikhali adliwayo, kude nomlilo, umthombo wokushisa.

Izinhlelo zokusebenza

6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydronaphthalen-2(1H)-oneiyisithinteli esimaphakathi se-Alectinib, i-anaplastic lymphoma kinase (ALK) inhibitor ekhetha kakhulu futhi enamandla ekwazi ukuvimba i-mutant yomgcini wesango ephikisayo, okuholela ekunciphiseni ukukhula kweseli.

Ifomu elingokomzimba

Uketshezi olungenambala ukuya kokuphuzi

Impilo yeshelufu

Ngokusho kokuhlangenwe nakho kwethu, umkhiqizo ungagcinwa izikhathi ezingu-12izinyanga kusukela ngosuku lokulethwa uma zigcinwe ezitsheni ezivalwe ngokuqinile, zivikelekile ekukhanyeni nasekushiseni futhi zigcinwe emazingeni okushisa aphakathi kuka-5 -30°C.

Tizakhiwo ezivamile

Iphuzu elibilayo

354.7±42.0 °C ku-760 mmHg

I-Flash Point

168.3±27.9 °C

IMisa ngqo

282.025543

I-PSA

26.30000

I-LogP

3.25

I-Vapor Pressure

0.0±0.8 mmHg ku-25°C

Inkomba ye-Refraction

1.545

pka

1.26±0.10(Okubikezelwe)

Ukuncibilika kwamanzi

50 mg/ml ku-CHCl3

 

 

Ukuphepha

Lapho uphatha lo mkhiqizo, sicela uthobele iseluleko nolwazi olunikezwe kudatha yezokuphepha futhi ubheke izindlela zokuvikela nenhlanzeko zasemsebenzini ezanele ukuphatha amakhemikhali.

 

Qaphela

Imininingwane equkethwe kulolu shicilelo isekelwe olwazini lwethu lwamanje nolwazi.Ngenxa yezinto eziningi ezingase zibe nomthelela ekucutshungulweni nasekusetshenzisweni komkhiqizo wethu, le datha ayikhululi abacubunguli ekwenzeni uphenyo nokuhlola kwabo;futhi le datha ayisho noma yisiphi isiqinisekiso sezinto ezithile, noma ukufaneleka komkhiqizo ngenjongo ethile.Noma yiziphi izincazelo, imidwebo, izithombe, idatha, izilinganiso, izisindo, njll. ezinikezwe lapha zingashintsha ngaphandle kolwazi lwangaphambili futhi azihlanganisi ikhwalithi yenkontileka okuvunyelwene ngayo yomkhiqizo.Ikhwalithi yenkontileka okuvunyelwene ngayo yomkhiqizo iphumela ngokukhethekile ezitatimendeni ezenziwe ekucacisweni komkhiqizo.Kuyisibopho somamukeli womkhiqizo wethu ukuqinisekisa ukuthi noma imaphi amalungelo obunikazi kanye nemithetho ekhona kanye nemithetho iyagcinwa.

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